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Mechanism of Pain Perception

The special sensory receptors called as nociceptors are present in our body. These receptors recognise the painful or unpleasant stimuli and then convert them into electrical signals, which are then sent to the brain.

The perception of pain is a four-step process. In the first step, the damaged tissue produces certain chemicals or hormones. These chemicals generate pain signals; the process is called transduction. The nerves to the brain carry these signals; this process is called transmission. The next step is perception, which involves the brain identifying the types of pain. The brain, then, sends signals to the affected region to react accordingly, this process is called descending modulation.